Which medication lowers blood pressure by targeting the vasomotor centers within the central nervous system?

Pharmacology MCQs for PPSC, FPSC, NTS, and Pakistan government job tests. Select an option below, then read the explanation.

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Subject
Pharmacologymedical-mcqs › pharmacology
Published
14 Jan 2023
Last updated
28 May 2026

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Explanation

Clonidine works by stimulating alpha-2 adrenergic receptors in the brainstem's vasomotor center, leading to reduced sympathetic outflow and decreased blood pressure. Unlike other antihypertensives such as labetalol (a beta-blocker), enalapril (an ACE inhibitor), or nifedipine (a calcium channel blocker), clonidine's primary action is central nervous system-mediated.

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