A resident doctor accidentally pricks herself with a suture needle previously used on a patient who has been HIV-positive for 11 years. The patient has adhered well to antiretroviral therapy and recently switched medications due to changes in physical appearance. His most recent CD4 count was 360 cells/mm³. What is the recommended post-exposure prophylaxis regimen for the doctor?
Explanation
The preferred post-exposure prophylaxis for healthcare workers exposed to HIV involves a combination of Zidovudine and Lamivudine. Adding a protease inhibitor or other antiretrovirals is not routinely recommended in this scenario. This dual therapy effectively reduces the risk of seroconversion following occupational exposure.