In the TNM staging system, what does the designation T3 indicate regarding the tumor size?

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Tumor larger than 2 centimetersTumor larger than 4 centimetersTumor measuring 4 centimeters with involvement of nearby tissuesTumor confined to its original location without spreadTumor smaller than 2 centimeters

Explanation

In TNM classification, T1 refers to tumors up to 2 cm, T2 to tumors larger than 2 cm but not exceeding 4 cm, and T3 indicates tumors exceeding 4 cm in size. T4 typically involves invasion into adjacent structures.