In which of the following processes does RNA NOT play a direct role?

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Modifications occurring after protein synthesisChanges made after RNA is transcribedDuplication of the DNA moleculeRemoval of introns from pre-mRNA

Explanation

RNA is directly involved in post-transcriptional modification, splicing, and other RNA-related processes. However, it does not participate directly in DNA replication, which is primarily carried out by DNA polymerases and related enzymes. Post-translation modifications happen to proteins after synthesis and do not involve RNA.