What is the most severe adverse effect associated with the use of chloramphenicol?

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Fungal infection such as candidiasisIncreased sensitivity to sunlightSuppression of bone marrow activitySwelling caused by angioneurotic edema

Explanation

The major and most dangerous side effect of chloramphenicol is bone marrow suppression, which can lead to serious blood disorders. Other side effects like candidiasis, photosensitivity, and angioneurotic edema are less severe in comparison.