What type of mutation occurs in sickle cell anemia when glutamine is substituted by valine in the beta chain?

Show Answers

Nonsense mutation affecting the beta chainMissense mutation in the beta chainBreakdown of the beta chainLoss of the beta chain segment

Explanation

In sickle cell anemia, the substitution of glutamine with valine in the beta globin chain is a missense mutation, where one amino acid is replaced by another, altering the protein's properties.