Which anxiolytic medication, used to treat generalized anxiety, does not act on the GABAergic system?

Explanation

Alprazolam, Diazepam, and Phenobarbital all exert their anxiolytic effects by enhancing the GABAergic system. In contrast, Buspirone is an anxiolytic that works through serotonin receptors and does not interact with the GABAergic pathway, making it distinct in its mechanism of action.