Which cofactor is essential for the activation of lipoprotein lipase?

Explanation

Lipoprotein lipase requires Apolipoprotein C-II as a cofactor to function properly. This apolipoprotein activates the enzyme, enabling it to hydrolyze triglycerides in lipoproteins. Other apolipoproteins, such as Apo A-II, Apo C-III, and Apo B-II, do not serve this activating role.