Which devastating epidemic struck London in 1625, worsening the economic crisis that marked the end of the Jacobean period between 1620 and 1626?

Explanation

The Jacobean era concluded amid a severe economic downturn from 1620 to 1626, which was further aggravated by a major outbreak of the bubonic plague in London in 1625. This deadly epidemic severely impacted the population and economy during that time.