Which enzyme does NOT use Acetyl Co-A as a substrate?

Explanation

Acetyl Co-A serves as a substrate for enzymes like HMG-CoA synthase, Malonyl CoA synthetase, and Fatty acid synthase. However, the malic enzyme does not use Acetyl Co-A as a substrate; instead, it catalyzes the oxidative decarboxylation of malate to pyruvate.