Which medication is effective for treating both intestinal and extraintestinal amoebiasis?

Explanation

Metronidazole is the drug of choice for managing both intestinal and extraintestinal amoebiasis due to its ability to eradicate the trophozoite form of Entamoeba histolytica. Diloxanide is primarily used as a luminal agent, while chloroquine and cefaclor are not effective against amoebiasis.