Which medication lowers blood pressure by targeting the vasomotor centers within the central nervous system?
Explanation
Clonidine works by stimulating alpha-2 adrenergic receptors in the brainstem's vasomotor center, leading to reduced sympathetic outflow and decreased blood pressure. Unlike other antihypertensives such as labetalol (a beta-blocker), enalapril (an ACE inhibitor), or nifedipine (a calcium channel blocker), clonidine's primary action is central nervous system-mediated.