Which metabolic process depends on NADPH as a necessary cofactor?

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Formation of glucose from non-carbohydrate sourcesBreakdown of glucose to pyruvateCreation of fatty acidsDegradation of glycogen to glucose

Explanation

NADPH is primarily utilized in anabolic reactions such as fatty acid synthesis, providing the reducing power needed. It is not required for gluconeogenesis, glycolysis, or glycogenolysis.