Which of the following statements about articaine is INCORRECT?

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Its plasma half-life is 90 minutesIt is an amide-type local anesthetic metabolized primarily in the liverMandibular infiltration provides better anesthesia than nerve block for mandibular molarsIncreased breakdown of the drug leads to higher toxicity

Explanation

Option A is incorrect because articaine has a plasma half-life of approximately 30 minutes, not 90 minutes. The other statements are accurate: articaine is an amide anesthetic metabolized in the liver; mandibular infiltration can be more effective than nerve block for molars; and greater metabolism can result in increased toxicity.