Which of the following statements about azole antifungal agents is incorrect?

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They exhibit fungistatic activity.They can cause liver toxicity.Drug resistance to azoles is frequently observed.They alter the metabolism of medications like cyclosporine, requiring a dosage decrease.

Explanation

Azoles are fungistatic and known to be hepatotoxic. Resistance to these drugs is common. However, azoles inhibit the metabolism of drugs such as cyclosporine, which typically necessitates a reduction, not an increase, in dosage.