Which of the following statements about cephalosporins is NOT true?

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They exhibit cross-reactivity with penicillin allergiesThey resist breakdown by penicillinase enzymesThey possess a wide range of activity but are ineffective against anaerobic bacteriaThey are commonly prescribed for infections of the upper respiratory tract

Explanation

Cephalosporins often cause allergic reactions in patients sensitive to penicillins (cross sensitivity). They have a broad antibacterial spectrum but generally lack activity against anaerobes. They are frequently used to treat upper respiratory tract infections. However, cephalosporins are not resistant to penicillinase enzymes; this characteristic is typical of penicillinase-resistant penicillins, not cephalosporins.