Which of the following statements about metformin is NOT correct?

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It suppresses mitochondrial cellular respirationIt is eliminated from the body via urine without metabolic changeIt decreases glucose synthesis in the liverIt is recommended for patients with severe heart failureNone of the above

Explanation

Metformin works by inhibiting mitochondrial respiration, is excreted unchanged through the kidneys, and lowers hepatic glucose production. However, it is contraindicated in patients with decompensated heart failure due to the risk of lactic acidosis.