Which of the following statements about pain is INCORRECT?

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Pain relief is linked to activation of μ and kappa opioid receptors.Dysphoria is related to stimulation of sigma receptors.NSAIDs provide relief by inhibiting the production of prostaglandins.Naloxone acts as a non-competitive antagonist and permanently blocks opioid receptors.

Explanation

Analgesia involves μ and kappa opioid receptors. Dysphoria is connected to sigma receptors. NSAIDs work by blocking prostaglandin synthesis. However, naloxone is a competitive antagonist that reversibly binds to opioid receptors, not a non-competitive or irreversible blocker.