Which of the following statements about Plummer-Vinson syndrome is true?

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It results from a lack of folic acidIt predominantly affects malesIt has no link to oral precancerous conditionsIt is closely connected with carcinoma of the post-cricoid regionIt primarily occurs in children

Explanation

Plummer-Vinson syndrome is more commonly seen in males. It is not caused by folic acid deficiency, is associated with oral premalignant lesions, and has a strong correlation with post-cricoid carcinoma.