Which of the following statements about prostaglandins and leukotrienes is INCORRECT?

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Prostaglandins and leukotrienes are produced from arachidonic acid metabolism.COX-1 enzyme expression is inducible in various tissues.Cytokines stimulate COX enzymes at inflammatory sites.Leukotrienes contribute to narrowing of the airways.Leukotrienes are involved in inflammatory responses.

Explanation

Arachidonic acid serves as the precursor for both prostaglandins and leukotrienes. COX-1 is generally constitutively expressed and not inducible, unlike COX-2 which is upregulated during inflammation by cytokines. Leukotrienes are known to cause bronchoconstriction, contributing to airway narrowing.