Which of the following statements about warfarin is incorrect?

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Warfarin can cause a temporary increase in clotting tendency.It is generally avoided during pregnancy due to the risk of fetal skeletal abnormalities.Within its racemic mixture, the R-enantiomer is four times more potent than the S-enantiomer.The anticoagulant effects typically become evident only after 72 hours of starting therapy.None of the above.

Explanation

Option C is incorrect because, in the racemic mixture of warfarin, the S-enantiomer is actually more potent than the R-enantiomer. The S-form is approximately three to five times more active than the R-form. Transient hypercoagulability (Option A) can occur initially, and warfarin is contraindicated in pregnancy due to fetal risks (Option B). The anticoagulant effect does take several days to manifest (Option D).