Which statement accurately describes the pathway of tetanus infection following a traumatic wound?

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Clostridium tetani spreads through nerves to reach the anterior horn cells of the spinal cord.The exotoxin tetanospasmin targets post-synaptic neurons and blocks nerve signal transmission.Tetanus toxoid should be administered intravenously to the patient.Tetanus infection results in a positive Nagler test.

Explanation

Clostridium tetani enters the body through wounds and travels along peripheral nerves to the anterior horn cells of the spinal cord. The tetanospasmin toxin acts on pre-synaptic neurons, not post-synaptic, to inhibit neurotransmitter release. Tetanus toxoid is given intramuscularly, not intravenously. The Nagler reaction is associated with Clostridium perfringens, not tetanus.