Why does Rifampicin cause oral contraceptives to fail in patients?

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Rifampicin increases the breakdown of contraceptive drugs.Rifampicin triggers the pituitary gland to release more gonadotropins.Rifampicin reduces the production of progestin hormones.Rifampicin blocks the effects of oral contraceptives.

Explanation

Rifampicin accelerates the metabolism of oral contraceptives by inducing liver enzymes, which lowers their effectiveness and can lead to contraceptive failure.